{"id":229984,"date":"2023-08-17T12:42:12","date_gmt":"2023-08-17T10:42:12","guid":{"rendered":"https:\/\/die-mundgesundheitsstiftung.de\/?page_id=229984"},"modified":"2024-04-30T11:56:03","modified_gmt":"2024-04-30T09:56:03","slug":"klassifikation-parodontitis","status":"publish","type":"page","link":"https:\/\/die-mundgesundheitsstiftung.de\/en\/stiftung\/klassifikation-parodontitis\/","title":{"rendered":"Classification of periodontitis"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; custom_padding_last_edited=&#8221;on|tablet&#8221; next_background_color=&#8221;#ffffff&#8221; _builder_version=&#8221;4.20.4&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#FFFFFF&#8221; background_image=&#8221;https:\/\/die-mundgesundheitsstiftung.de\/media\/2023\/08\/DMS-9.png&#8221; parallax=&#8221;on&#8221; custom_padding=&#8221;212px||212px||true|&#8221; custom_padding_tablet=&#8221;180px||180px||true|false&#8221; 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button_bg_enable_color__hover=&#8221;on&#8221; button_text_color__hover_enabled=&#8221;on|desktop&#8221; button_text_color__hover=&#8221;#FFFFFF&#8221; button_border_color__hover_enabled=&#8221;on|hover&#8221; button_border_color__hover=&#8221;RGBA(255,255,255,0)&#8221;][\/dipi_button_grid_child][\/dipi_button_grid][dipi_flip_box front_title=&#8221;Vorteile der Mitgliedschaft&#8221; use_front_icon=&#8221;on&#8221; front_icon=&#8221;&#xf3a5;||fa||400&#8243; front_icon_color=&#8221;#000000&#8243; front_content=&#8221;<\/p>\n<p>Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam nonumy eirmod tempor invidunt ut labore et dolore<\/p>\n<p>&#8221; back_title=&#8221;Wer wir sind&#8221; use_back_icon=&#8221;on&#8221; back_icon=&#8221;&#xf3a5;||fa||400&#8243; back_icon_color=&#8221;#FFFFFF&#8221; back_content=&#8221;<\/p>\n<p>Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam nonumy eirmod tempor invidunt ut labore et dolore<\/p>\n<p>&#8221; use_force_square=&#8221;on&#8221; front_side_bg_color=&#8221;#F5F5F5&#8243; back_side_bg_color=&#8221;#FE5E15&#8243; _builder_version=&#8221;4.22.1&#8243; _module_preset=&#8221;default&#8221; front_title_font=&#8221;|600|||||||&#8221; front_title_text_color=&#8221;#000000&#8243; front_desc_text_color=&#8221;#000000&#8243; front_desc_line_height=&#8221;2em&#8221; back_title_font=&#8221;|600|||||||&#8221; back_title_text_color=&#8221;#FFFFFF&#8221; back_desc_text_color=&#8221;#F5F5F5&#8243; back_desc_line_height=&#8221;2em&#8221; custom_margin=&#8221;0px||||false|false&#8221; custom_padding=&#8221;0px||3px||false|false&#8221; custom_padding_tablet=&#8221;|120px||120px|false|true&#8221; custom_padding_phone=&#8221;|10px||10px|false|true&#8221; custom_padding_last_edited=&#8221;on|tablet&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221; overlay_bg_color_gradient_type_tablet=&#8221;linear&#8221; overlay_bg_color_gradient_type_phone=&#8221;linear&#8221; overlay_bg_color_gradient_type__hover=&#8221;linear&#8221; image_bg_color_gradient_type__hover=&#8221;linear&#8221;][\/dipi_flip_box][\/et_pb_column][et_pb_column type=&#8221;2_3&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.20.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><span>The new, globally valid classification of periodontal diseases requires a rethink in the understanding of the disease process and diagnostics<\/span><\/p>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.20.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<div id=\"fws_64ddcad8c9d80\" data-midnight=\"\" data-column-margin=\"default\" class=\"wpb_row vc_row-fluid vc_row inner_row\">\n<div class=\"row_col_wrap_12_inner col span_12  left\">\n<div class=\"vc_col-sm-12 wpb_column column_container vc_column_container col child_column no-extra-padding inherit_tablet inherit_phone\" data-padding-pos=\"all\" data-has-bg-color=\"false\" data-bg-color=\"\" data-bg-opacity=\"1\" data-animation=\"\" data-delay=\"0\">\n<div class=\"vc_column-inner\">\n<div class=\"wpb_wrapper\">\n<div class=\"nectar-split-heading animated-in\" data-align=\"default\" data-m-align=\"inherit\" data-text-effect=\"default\" data-animation-type=\"default\" data-animation-delay=\"0\" data-animation-offset=\"\" data-m-rm-animation=\"\" data-stagger=\"\" data-custom-font-size=\"false\">\n<div class=\"heading-line\">\n<div id=\"fws_64ddf6d24a7d9\" data-midnight=\"\" data-column-margin=\"default\" class=\"wpb_row vc_row-fluid vc_row inner_row\">\n<div class=\"row_col_wrap_12_inner col span_12  left\">\n<div class=\"vc_col-sm-12 wpb_column column_container vc_column_container col child_column no-extra-padding inherit_tablet inherit_phone\" data-padding-pos=\"all\" data-has-bg-color=\"false\" data-bg-color=\"\" data-bg-opacity=\"1\" data-animation=\"\" data-delay=\"0\">\n<div class=\"vc_column-inner\">\n<div class=\"wpb_wrapper\">\n<div class=\"nectar-split-heading animated-in\" data-align=\"default\" data-m-align=\"inherit\" data-text-effect=\"default\" data-animation-type=\"default\" data-animation-delay=\"0\" data-animation-offset=\"\" data-m-rm-animation=\"\" data-stagger=\"\" data-custom-font-size=\"false\">\n<div class=\"heading-line\">\n<div id=\"fws_64ddf76b069e9\" data-midnight=\"\" data-column-margin=\"default\" class=\"wpb_row vc_row-fluid vc_row inner_row\">\n<div class=\"row_col_wrap_12_inner col span_12  left\">\n<div class=\"vc_col-sm-12 wpb_column column_container vc_column_container col child_column no-extra-padding inherit_tablet inherit_phone\" data-padding-pos=\"all\" data-has-bg-color=\"false\" data-bg-color=\"\" data-bg-opacity=\"1\" data-animation=\"\" data-delay=\"0\">\n<div class=\"vc_column-inner\">\n<div class=\"wpb_wrapper\">\n<div class=\"nectar-split-heading animated-in\" data-align=\"default\" data-m-align=\"inherit\" data-text-effect=\"default\" data-animation-type=\"default\" data-animation-delay=\"0\" data-animation-offset=\"\" data-m-rm-animation=\"\" data-stagger=\"\" data-custom-font-size=\"false\">\n<div class=\"heading-line\">\n<div id=\"fws_64ddf8bb78138\" data-midnight=\"\" data-column-margin=\"default\" class=\"wpb_row vc_row-fluid vc_row inner_row\">\n<div class=\"row_col_wrap_12_inner col span_12  left\">\n<div class=\"vc_col-sm-12 wpb_column column_container vc_column_container col child_column no-extra-padding inherit_tablet inherit_phone\" data-padding-pos=\"all\" data-has-bg-color=\"false\" data-bg-color=\"\" data-bg-opacity=\"1\" data-animation=\"\" data-delay=\"0\">\n<div class=\"vc_column-inner\">\n<div class=\"wpb_wrapper\">\n<div class=\"nectar-split-heading animated-in\" data-align=\"default\" data-m-align=\"inherit\" data-text-effect=\"default\" data-animation-type=\"default\" data-animation-delay=\"0\" data-animation-offset=\"\" data-m-rm-animation=\"\" data-stagger=\"\" data-custom-font-size=\"false\">\n<div class=\"heading-line\">\n<div>\n<h5><span>Early detection and prevention<\/span><\/h5>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div id=\"fws_64ddf8bb78597\" data-midnight=\"\" data-column-margin=\"default\" class=\"wpb_row vc_row-fluid vc_row inner_row  vc_custom_1643712426459\">\n<div class=\"row-bg-wrap\">\n<div class=\"row-bg\"><\/div>\n<\/div>\n<div class=\"row_col_wrap_12_inner col span_12  left\">\n<div class=\"vc_col-sm-12 wpb_column column_container vc_column_container col child_column no-extra-padding inherit_tablet inherit_phone\" data-padding-pos=\"all\" data-has-bg-color=\"false\" data-bg-color=\"\" data-bg-opacity=\"1\" data-animation=\"\" data-delay=\"0\">\n<div class=\"vc_column-inner\">\n<div class=\"wpb_wrapper\">\n<div class=\"nectar-split-heading animated-in\" data-align=\"default\" data-m-align=\"inherit\" data-text-effect=\"default\" data-animation-type=\"default\" data-animation-delay=\"0\" data-animation-offset=\"\" data-m-rm-animation=\"\" data-stagger=\"\" data-custom-font-size=\"false\">\n<div class=\"heading-line\">\n<div>\n<h3><span>PA classification 2018: staging and grading<\/span><\/h3>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div id=\"fws_64ddf8bb78908\" data-midnight=\"\" data-column-margin=\"default\" class=\"wpb_row vc_row-fluid vc_row inner_row  vc_custom_1547720698310\">\n<div class=\"row-bg-wrap\">\n<div class=\"row-bg\"><\/div>\n<\/div>\n<div class=\"row_col_wrap_12_inner col span_12  left\">\n<div class=\"vc_col-sm-6 wpb_column column_container vc_column_container col child_column has-animation padding-3-percent inherit_tablet inherit_phone triggered-animation animated-in\" data-padding-pos=\"top-bottom\" data-has-bg-color=\"false\" data-bg-color=\"\" data-bg-opacity=\"1\" data-animation=\"fade-in-from-bottom\" data-delay=\"0\">\n<div class=\"vc_column-inner\">\n<div class=\"wpb_wrapper\">\n<div class=\"wpb_text_column wpb_content_element\">\n<div class=\"wpb_wrapper\">\n<p class=\"p2\"><span class=\"s1\">Periodontal disease usually develops gradually. It can take decades before manifest periodontitis is diagnosed -<span class=\"Apple-converted-space\">\u00a0<span>\u00a0<\/span><\/span>and treated. As t<\/span><span class=\"s2\">he authors of the latest Barmer Dental Report (2017) found, periodontitis is treated so late in many patients that even adequate treatment can no longer prevent tooth loss.<\/span><\/p>\n<p class=\"p2\"><span class=\"s2\">One of the reasons for this is the diagnostic procedure: U<\/span><span class=\"s1\">ntil now, the focus has been on the extent of degeneration (probing depth, bleeding on probing, etc.), but not on the onset of collagenolytic destruction of the periodontal tissue.<\/span><\/p>\n<p class=\"p2\"><span class=\"s1\">With the introduction of the new, globally standardized periodontitis classification on June 21, 2018, the focus will be placed more on the development and progression of periodontitis:<br \/>The comprehensive classification is based on the latest evidence and is based on the classifications commonly used by the WHO, e.g. for cancer (Caton et al. 2018). For periodontitis, this includes a decision matrix with a \"staging and grading\" system (Tonetti et al. 2018).<\/span><\/p>\n<p><span class=\"s1\"><b><span>The extent of the periodontitis is defined in staging<\/span><br \/><\/b><\/span><span class=\"s1\">The staging comprises four stages from stage 1<span>\u00a0<\/span><span>(minor<\/span><span>\u00a0<\/span>periodontal disease) to stage 4 (severe periodontal disease).<\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"vc_col-sm-6 wpb_column column_container vc_column_container col child_column has-animation padding-3-percent inherit_tablet inherit_phone triggered-animation animated-in\" data-padding-pos=\"top-bottom\" data-has-bg-color=\"false\" data-bg-color=\"\" data-bg-opacity=\"1\" data-animation=\"fade-in-from-bottom\" data-delay=\"0\">\n<div class=\"vc_column-inner\">\n<div class=\"wpb_wrapper\">\n<div class=\"wpb_text_column wpb_content_element\">\n<div class=\"wpb_wrapper\">\n<p class=\"p2\"><span class=\"s1\">The stage of periodontitis is determined by clinical and radiographic findings, such as clinical attachment loss, radiographic bone loss, probing depths, vertical defects and furcation involvement, tooth mobility and tooth loss.<\/span><\/p>\n<p class=\"p1\"><span class=\"s1\"><b><span>The progression of periodontitis is defined in grading<\/span><br \/><\/b><\/span><span class=\"s1\">The risk of disease and the degree of progression are divided into three levels, from level A (lowest risk or slow progression) to level C (highest risk or rapid progression). Risk factors such as smoking and concomitant diseases, e.g. diabetes, can be taken into account.\u00a0<\/span><\/p>\n<p class=\"p1\"><span class=\"s1\">The new staging and grading matrix, which replaces the previous classification into \"aggressive\" and \"chronic\" periodontitis, offers great advantages in terms of individualized diagnosis and therefore also treatment. If it is possible to identify at-risk patients reliably and at an early stage, this simple but effective approach can be a great opportunity to reduce the prevalence of periodontal disease.<\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][dipi_carousel navigation=&#8221;on&#8221; navigation_on_hover=&#8221;on&#8221; navigation_prev_icon_yn=&#8221;on&#8221; navigation_prev_icon=&#8221;&#x34;||divi||400&#8243; navigation_next_icon_yn=&#8221;on&#8221; navigation_next_icon=&#8221;&#x35;||divi||400&#8243; navigation_size=&#8221;20&#8243; navigation_padding=&#8221;20&#8243; navigation_color=&#8221;#FFFFFF&#8221; navigation_bg_color=&#8221;#FE5E15&#8243; navigation_circle=&#8221;on&#8221; navigation_position_right=&#8221;-40px&#8221; columns_tablet=&#8221;2&#8243; columns_phone=&#8221;1&#8243; columns_last_edited=&#8221;on|tablet&#8221; navigation_position_left_tablet=&#8221;-40px&#8221; navigation_position_left_phone=&#8221;-25px&#8221; navigation_position_left_last_edited=&#8221;on|tablet&#8221; navigation_position_right_tablet=&#8221;-40px&#8221; navigation_position_right_phone=&#8221;-25px&#8221; navigation_position_right_last_edited=&#8221;on|tablet&#8221; _builder_version=&#8221;4.20.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][dipi_carousel_child title_text=&#8221;Implant Safe Center&#8221; desc_text=&#8221;<\/p>\n<p>Pellentesque tincidunt text of the elit dapibus lacus sodales dummy sed industry<\/p>\n<p>&#8221; img_width=&#8221;64px&#8221; _builder_version=&#8221;4.20.4&#8243; _module_preset=&#8221;default&#8221; title_font=&#8221;|600|||||||&#8221; title_font_size=&#8221;18px&#8221; desc_line_height=&#8221;2em&#8221; background_color=&#8221;#F5F5F5&#8243; background_enable_color=&#8221;on&#8221; custom_padding=&#8221;20px||20px||true|false&#8221; global_colors_info=&#8221;{}&#8221;][\/dipi_carousel_child][dipi_carousel_child title_text=&#8221;Oral Fitness Coach&#8221; desc_text=&#8221;<\/p>\n<p>Pellentesque tincidunt text of the elit dapibus lacus sodales dummy sed industry<\/p>\n<p>&#8221; img_width=&#8221;64px&#8221; _builder_version=&#8221;4.20.4&#8243; _module_preset=&#8221;default&#8221; title_font=&#8221;|600|||||||&#8221; title_font_size=&#8221;18px&#8221; desc_line_height=&#8221;2em&#8221; background_color=&#8221;#F5F5F5&#8243; background_enable_color=&#8221;on&#8221; custom_padding=&#8221;20px||20px||true|false&#8221; global_colors_info=&#8221;{}&#8221;][\/dipi_carousel_child][dipi_carousel_child title_text=&#8221;Oral Fitness Center&#8221; desc_text=&#8221;<\/p>\n<p>Pellentesque tincidunt text of the elit dapibus lacus sodales dummy sed industry<\/p>\n<p>&#8221; img_width=&#8221;64px&#8221; _builder_version=&#8221;4.20.4&#8243; _module_preset=&#8221;default&#8221; title_font=&#8221;|600|||||||&#8221; title_font_size=&#8221;18px&#8221; desc_line_height=&#8221;2em&#8221; background_color=&#8221;#F5F5F5&#8243; background_enable_color=&#8221;on&#8221; custom_padding=&#8221;20px||20px||true|false&#8221; global_colors_info=&#8221;{}&#8221;][\/dipi_carousel_child][dipi_carousel_child title_text=&#8221;G\u00fctesiegel&#8221; desc_text=&#8221;<\/p>\n<p>Pellentesque tincidunt text of the elit dapibus lacus sodales dummy sed industry<\/p>\n<p>&#8221; img_width=&#8221;64px&#8221; _builder_version=&#8221;4.20.4&#8243; _module_preset=&#8221;default&#8221; title_font=&#8221;|600|||||||&#8221; title_font_size=&#8221;18px&#8221; desc_line_height=&#8221;2em&#8221; background_color=&#8221;#F5F5F5&#8243; background_enable_color=&#8221;on&#8221; custom_padding=&#8221;20px||20px||true|false&#8221; global_colors_info=&#8221;{}&#8221;][\/dipi_carousel_child][\/dipi_carousel][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=&#8221;4.20.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.20.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.20.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<div id=\"fws_64ddf84525b25\" data-midnight=\"\" data-column-margin=\"default\" class=\"wpb_row vc_row-fluid vc_row inner_row\">\n<div class=\"row_col_wrap_12_inner col span_12  left\">\n<div class=\"vc_col-sm-12 wpb_column column_container vc_column_container col child_column no-extra-padding inherit_tablet inherit_phone\" data-padding-pos=\"all\" data-has-bg-color=\"false\" data-bg-color=\"\" data-bg-opacity=\"1\" data-animation=\"\" data-delay=\"0\">\n<div class=\"vc_column-inner\">\n<div class=\"wpb_wrapper\">\n<div class=\"nectar-split-heading animated-in\" data-align=\"default\" data-m-align=\"inherit\" data-text-effect=\"default\" data-animation-type=\"default\" data-animation-delay=\"0\" data-animation-offset=\"\" data-m-rm-animation=\"\" data-stagger=\"\" data-custom-font-size=\"false\">\n<div class=\"heading-line\">\n<div id=\"fws_64ddf8bb7b09c\" data-midnight=\"\" data-column-margin=\"default\" class=\"wpb_row vc_row-fluid vc_row inner_row\">\n<div class=\"row_col_wrap_12_inner col span_12  left\">\n<div class=\"vc_col-sm-12 wpb_column column_container vc_column_container col child_column no-extra-padding inherit_tablet inherit_phone\" data-padding-pos=\"all\" data-has-bg-color=\"false\" data-bg-color=\"\" data-bg-opacity=\"1\" data-animation=\"\" data-delay=\"0\">\n<div class=\"vc_column-inner\">\n<div class=\"wpb_wrapper\">\n<div class=\"nectar-split-heading animated-in\" data-align=\"default\" data-m-align=\"inherit\" data-text-effect=\"default\" data-animation-type=\"default\" data-animation-delay=\"0\" data-animation-offset=\"\" data-m-rm-animation=\"\" data-stagger=\"\" data-custom-font-size=\"false\">\n<div class=\"heading-line\">\n<div>\n<h5><span>Detecting active oral collagen degradation with the help of aMMP-8<\/span><\/h5>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div id=\"fws_64ddf8bb7b3e7\" data-midnight=\"\" data-column-margin=\"default\" class=\"wpb_row vc_row-fluid vc_row inner_row  vc_custom_1643712453695\">\n<div class=\"row-bg-wrap\">\n<div class=\"row-bg\"><\/div>\n<\/div>\n<div class=\"row_col_wrap_12_inner col span_12  left\">\n<div class=\"vc_col-sm-12 wpb_column column_container vc_column_container col child_column no-extra-padding inherit_tablet inherit_phone\" data-padding-pos=\"all\" data-has-bg-color=\"false\" data-bg-color=\"\" data-bg-opacity=\"1\" data-animation=\"\" data-delay=\"0\">\n<div class=\"vc_column-inner\">\n<div class=\"wpb_wrapper\">\n<div class=\"nectar-split-heading animated-in\" data-align=\"default\" data-m-align=\"inherit\" data-text-effect=\"default\" data-animation-type=\"default\" data-animation-delay=\"0\" data-animation-offset=\"\" data-m-rm-animation=\"\" data-stagger=\"\" data-custom-font-size=\"false\">\n<div class=\"heading-line\">\n<div>\n<h3><span>Early detection is the best prevention<\/span><\/h3>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div id=\"fws_64ddf8bb7b761\" data-midnight=\"\" data-column-margin=\"default\" class=\"wpb_row vc_row-fluid vc_row inner_row  vc_custom_1547720774702\">\n<div class=\"row-bg-wrap\">\n<div class=\"row-bg\"><\/div>\n<\/div>\n<div class=\"row_col_wrap_12_inner col span_12  left\">\n<div class=\"vc_col-sm-12 wpb_column column_container vc_column_container col child_column has-animation padding-3-percent inherit_tablet inherit_phone triggered-animation animated-in\" data-padding-pos=\"top-bottom\" data-has-bg-color=\"false\" data-bg-color=\"\" data-bg-opacity=\"1\" data-animation=\"fade-in-from-bottom\" data-delay=\"0\">\n<div class=\"vc_column-inner\">\n<div class=\"wpb_wrapper\">\n<div class=\"wpb_text_column wpb_content_element\">\n<div class=\"wpb_wrapper\">\n<p class=\"p1\"><span class=\"s1\">PerioSafe<\/span><span class=\"s1\"><span>\u00a0<\/span>DRS offers the possibility of rapid quantitative determination of the risk of periodontal disease and its progression. This is because PerioSafe<\/span><span class=\"s2\"><b><sup>\u00a9<\/sup><\/b><\/span><span class=\"s1\"><span>\u00a0<\/span>DRS detects the enzyme aMMP-8, which is a biomarker for the breakdown of the collagen network of the periodontium. With immunological prevention diagnostics, a distinction can be made between no or only a very low risk and an increased risk of periodontal tissue loss.<\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; specialty=&#8221;on&#8221; padding_top_2=&#8221;50px&#8221; padding_right_2=&#8221;50px&#8221; padding_bottom_2=&#8221;50px&#8221; padding_left_2=&#8221;50px&#8221; padding_top_bottom_link_2=&#8221;true&#8221; padding_left_right_link_2=&#8221;true&#8221; padding_2_tablet=&#8221;&#8221; padding_2_phone=&#8221;30px|20px|30px|20px|true|true&#8221; padding_2_last_edited=&#8221;on|phone&#8221; custom_css_main_2=&#8221;box-shadow: 0px 2px 18px 0px rgb(100 130 208 \/ 17%);&#8221; _builder_version=&#8221;4.20.4&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;58px|||||&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; specialty_columns=&#8221;2&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_row_inner _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column_inner saved_specialty_column_type=&#8221;1_2&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][dipi_dual_heading first_heading=&#8221;von den Vorteilen profitieren&#8221; use_background_text=&#8221;on&#8221; background_text=&#8221;Dabei sein&#8221; fh_padding=&#8221;0px|10px|0px|10px|false|true&#8221; bt_position_vertical=&#8221;25%&#8221; bt_style=&#8221;stroke&#8221; bt_stroke_color=&#8221;#e9ecef&#8221; bt_stroke_fill=&#8221;RGBA(255,255,255,0)&#8221; background_text_color_gradient_direction=&#8221;90deg&#8221; background_text_color_gradient_stops=&#8221;#00235a 0%|#7d8aa1 100%&#8221; background_text_color_gradient_start=&#8221;#00235a&#8221; background_text_color_gradient_end=&#8221;#7d8aa1&#8243; bt_padding=&#8221;0px|0px|0px||false|false&#8221; bt_margin=&#8221;|0px|0px|10px|false|false&#8221; _builder_version=&#8221;4.20.4&#8243; _module_preset=&#8221;default&#8221; first_heading_text_color=&#8221;#FE5E15&#8243; first_heading_font_size=&#8221;14px&#8221; first_heading_letter_spacing=&#8221;3px&#8221; background_text_font=&#8221;|||on|||||&#8221; background_text_text_align=&#8221;left&#8221; background_text_font_size=&#8221;80px&#8221; text_orientation=&#8221;left&#8221; custom_margin=&#8221;||||false|false&#8221; background_text_font_size_tablet=&#8221;80px&#8221; background_text_font_size_phone=&#8221;50px&#8221; background_text_font_size_last_edited=&#8221;on|phone&#8221; background_text_line_height_phone=&#8221;2.6em&#8221; background_text_line_height_last_edited=&#8221;off|phone&#8221; custom_css_main_element=&#8221;margin-bottom: 25px !important;&#8221; border_color_left=&#8221;#FE5E15&#8243; border_width_left_bt_border=&#8221;5px&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221; background_text_text_color__hover_enabled=&#8221;off|desktop&#8221; overlay_bg_color_gradient_type_tablet=&#8221;linear&#8221; overlay_bg_color_gradient_type_phone=&#8221;linear&#8221; overlay_bg_color_gradient_type__hover=&#8221;linear&#8221; image_bg_color_gradient_type__hover=&#8221;linear&#8221;][\/dipi_dual_heading][et_pb_text _builder_version=&#8221;4.20.4&#8243; _module_preset=&#8221;default&#8221; header_2_font=&#8221;|700|||||||&#8221; header_2_font_size=&#8221;35px&#8221; header_2_line_height=&#8221;1.5em&#8221; custom_margin=&#8221;||10px||false|false&#8221; header_2_font_size_tablet=&#8221;35px&#8221; header_2_font_size_phone=&#8221;28px&#8221; header_2_font_size_last_edited=&#8221;on|phone&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2>Become a supporting member<\/h2>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.22.1&#8243; _module_preset=&#8221;default&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam nonumy eirmod tempor invidunt ut labore et dolore magna aliquyam erat, sed diam voluptua. At vero eos et accusam et<\/p>\n<p>[\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][et_pb_row_inner column_structure=&#8221;1_2,1_2&#8243; use_custom_gutter=&#8221;on&#8221; gutter_width=&#8221;2&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;0px||0px||true|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column_inner type=&#8221;1_2&#8243; saved_specialty_column_type=&#8221;1_2&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_blurb title=&#8221;Netzwerk&#8221; use_icon=&#8221;on&#8221; font_icon=&#8221;&#xf14a;||fa||900&#8243; icon_color=&#8221;#FE5E15&#8243; icon_placement=&#8221;left&#8221; image_icon_width=&#8221;15px&#8221; _builder_version=&#8221;4.20.4&#8243; _module_preset=&#8221;default&#8221; header_text_color=&#8221;#333333&#8243; header_font_size=&#8221;14px&#8221; header_line_height=&#8221;1.1em&#8221; 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