Human medicine

Oncology

Advantages of membership

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Who we are

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How healthy are your cancer patients' mouths?

Health begins in the mouth

Scientific studies indicate that a long-standing chronic inflammatory status of the periodontal tissue can be an independent risk factor for the development of cancer. For example, specific pathogens such as Porphyromonas gingivalis have been shown to prevent cell apoptosis and thus promote the development of cancer - locally and remotely. Low-grade inflammatory processes in particular (low grade inflammation) are thought to be involved in cancer development (Aran 2016).

Numerous international studies have shown links between periodontal disease and

  • Breast cancer
  • Colorectal cancer
  • Pancreatic cancer
  • Prostate cancer
  • Head and neck cancer
  • Uterine cancer
  • Types of blood cancer (lymphomas)
Possible complications

Is there a need for action?

Yes, for cancer patients and patients with an increased risk of carcinoma, because ...

  • periodontitis in cancer patients is associated with increased overall mortality (Heikkilä 2018).
  • the risk of lung and bowel cancer is increased in people with periodontitis.
  • poor oral hygiene can increase the risk of some types of cancer, such as pancreatic cancer (Huang 2016).
  • tooth loss is significantly associated with a higher risk of cancer (Shi 2018).
  • in many cancer patients, oral hygiene is not optimal, which is a risk factor for periodontal disease.
aMMP-8

Expanding prevention diagnostics with aMMP-8

Recent studies indicate that good oral hygiene and plaque removal as well as measures against periodontitis may reduce the risk of colorectal cancer and other types of cancer (Heliyon 2018).

With the PerioSafe DR test, internists and general practitioners can now easily test their patients for active oral collagen degradation in the practice. As a check-up to identify patients at risk of periodontitis, PerioSafe DR is an ideal addition to the internal medicine practice prevention program.

With PerioSafe 

Advanced diagnostics with PerioSafe

  • With PerioSafe DR, clinicians can detect active oral collagen degradation at a reversible stage, i.e. before the gums appear clinically conspicuous
  • PerioSafe DR is particularly suitable for patients with an increased risk of carcinoma
  • PerioSafe DR is easy and reliable to use in the internal medicine practice (saliva sample)

Oral health is particularly important for:

  • Patients with an increased risk of carcinoma,
    e.g. patients with ulcerative colitis or Crohn's disease
  • All patients who want to do more for their (oral) health as a preventive measure

What to do if the value is high?

In the event of a finding, a referral to a periodontist or specialist dentist for periodontology is advisable as part of an interdisciplinary collaboration. Patients should be informed about the risks of a possibly incipient or manifest chronic periodontal inflammation in connection with their individual health situation.

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Dirk-Rolf Gieselmann

Dirk-Rolf Gieselmann

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